Phage Directory, expanded
Dear phage fans,
You may have noticed some improvements and differences around the site, and we have some exciting news to share! We’ve heard lots of feedback over the past year, and we’ve made some additions and improvements based on what we’ve heard from the phage community. Plus, we’ve received funding to move forward with this work!
Read more about our expanded mission and how we got here.
Please let us know how we’re doing and send us questions and suggestions!
— Jan & Jessica
More focus on phage research and development
Expanded access to phage therapy starts with phage research, clinical trials, data collection, publication, and the collective hard work of the entire phage community.
Phage Directory is expanding its platform to support the community of phage researchers and phage developers in a few ways:
Profiles for phage researchers, labs and organizations
Phage Directory is growing beyond tracking labs for phage therapy. We want to help you find collaborators in the phage community, follow what others are working on, and get noticed for your specific expertise.
Join the Directory if you work with phages, whether you’re a principal investigator, postdoc, student, industry scientist, or whatever your role in the phage world may be.
Add your organization if you’re a phage startup or biotech, phage bank, nonprofit, CRO, or an organization that works with phages in any way.
Capsid & Tail is now easier to read and cite
Each article is now easier to read and to cite, and our guest writers can easily get credit for their work. All changes apply to past issues too!
Easily post a job, event, or a message to the Community
To support our growing phage biotech community, all job posts are now free.
Support from Mozilla!
We’re thrilled to announce that we’ve been awarded a Mozilla Open Science Mini-Grant! We’re extremely grateful to Mozilla and to the Leona M. and Harry B. Helmsley Charitable Trust for getting behind our vision and supporting us as we build the infrastructure to accelerate progress in the phage field through increased openness and collaboration.
With this grant, Phage Directory is funded to begin developing an open source and open access phage tracking and phage data publication platform.
Let’s bring phage data and insights online
Our goal is to bring the world’s known phages and associated metadata online, and to make the data open and discoverable. This means ALL phages—not just those useful for therapy.
1. Contribute to an open phage database
Get noticed for what you do, help potential collaborators find you, and help your global peers by listing your lab’s phages along with their associated characteristics, papers and patents.
If you’d like to bring your lab’s phage data online, please email us at firstname.lastname@example.org and we’ll be in touch soon.
If you’re concerned about sharing information about your phages, we’d love to hear your perspective too. What kinds of phage data should be public, and what should be private? Is there anything we can do to make you feel more comfortable listing your phages and sharing your insights? Let us know by emailing email@example.com.
2. Get your phage insights published
Publish open access, peer-reviewed phage genome reports and phage characterization reports. We are now open for submissions!
Thinking of attending Phage Futures EU in Brussels this September? Tomorrow (Friday, July 26) is your last chance for early bird rates! Register here & use PD10 for 10% off!
Before now, no virus has been reported to infect ammonia-oxidizing archaea (AOA) from the phylum Thaumarchaeota (ubiquitous marine archaea). However, a new paper by Jong-Geol Kim (Chungbuk National Univ.) and colleagues describes the isolation and characterization of three Nitrosopumilus spindle-shaped viruses that infect AOA. Curiously, viral replication inhibits AOA growth and reduces ammonia oxidation and nitrite reduction, but does not degrade the host chromosome or decrease cell counts.
Wondering about the infective capacity of the phages that make up the gut viromes you’re analyzing? Ling Deng (Univ. of Copenhagen) and colleagues have developed an efficient protocol for the extraction of infective viruses from low volume fecal samples. They detect infective viruses from the same samples used for metagenomic sequencing, and they report extracting 48 viromes per working day, with less than 4 h of hands-on time!
Alfred Fillol-Salom (Univ. of Glasgow) and colleagues have uncovered how Gram-negative phage-inducible chromosomal islands (PICIs), a universal class of mobile genetic elements that impact bacterial virulence, hijack phage machinery for their own packaging.