The Phage Directory Slack Community

Issue 166 | March 4, 2022
6 min read
Capsid and Tail

Did you know there are over 500 phage phriends who hang out in the Phage Directory Slack community? Today, undergraduate phage enthusiast Sayde Perry shares info about the Slack, how to get involved, and what to expect.

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What’s New

Clinical trial: Armata Pharmaceuticals announces clearance of investigational new drug application to initiate phase 2 clinical trial of AP-PA02 in non-cystic fibrosis bronchiectasis.

Clinical TrialPhage Therapy

Paper: RNA targeting with CRISPR-Cas13a facilitates bacteriophage genome engineering

CRISPR-Cas SystemPhage engineeringResearch paper

Paper: Bacteriophage therapy as a treatment option for complex cardiovascular implant infection - The German Heart Center Berlin experience.

Phage TherapyResearch paper

Paper: Phage banks as potential tools to rapidly and cost-effectively manage antimicrobial resistance in the developing world

AMRBiobankResearch paper

Article: Can Phages Help Where Antibiotics Have Failed? By Dr. Judy Stone, MD

Antibiotic resistant bacteriaTop articles

Latest Jobs

Microbe-phage interactionsMolecular BiologyPost Doc
Postdoc: Join a multidisciplinary team using microbiology and molecular biology techniques to investigate relationships between bacteria and their viruses, bacteriophages.
Microbial ecologyResearch Associate
Research Associate: Work in the Centre for Molecular Bacteriology and Infection (CMBI) to focus on the mechanisms of dissemination of Aspergillus fumigatus from the lung.
Phage encapsulationSenior Research Scientist
Senior Research Assistant: Investigate nanoparticle encapsulation of phages for improved activity against bacteria.
Genome annotationGenome sequencingResearch Assistant
Research Assistant: Implement novel and existing Next-Generation Sequencing (NGS) applications, including assembly and annotation of bacterial and phage genomes.

Community Board

Anyone can post a message to the phage community — and it could be anything from collaboration requests, post-doc searches, sequencing help — just ask!

iVoM Season 2, episode #5: Environmental impact of virus-host interactions
Date: 2 pm CET, Tuesday, March 15th, 2022
Register at https://ivom.phage.directory

Coupling metagenomics to correlative microscopy for identification of novel viruses in the deep biosphere
Prof. Alexander Probst
University of Duisburg-Essen, Germany

From phage to shark: microbial and macrobial predation govern state transitions on coral reefs
Dr. Cynthia Silveira
International Center for Genetic Engineering and Biotechnology (ICGEB)

Harnessing virus for alleviating plant stress
Dr. Neeti Sanan-Mishra
International Center for Genetic Engineering and Biotechnology (ICGEB)

Chairs
Dr. Matthias Fischer
Max Planck Institute for Medical Research, Heidelberg, Germany

Prof. Corina Brussaard
Royal Netherlands Institute for Sea Research, Netherlands

Virtual EventiVoMViruses of Microbes

The first ESGNTA Online Course titled: “Personalised Phage Therapy: Basic Principles of Monitoring and Treatment”, will take place virtually on the 7-10th of June 2022.

It will include four sessions with cutting-edge scientific talks in the field of personalised phage therapy, including (1) therapeutic monitoring, (2) immune response to bacteriophages, (3) formulation and administration of bacteriophages for therapy, and (4) current state and prospects of oral phage therapy.

Register here by June 1 2022.

Online coursePhage Therapy

Phage Directory’s new structured peer feedback platform, Instill Science, is live!

Would you jump on a 30 min zoom call to help a fellow phage researcher talk through a problem? Or provide second set of eyes on someone’s work?

Check if there’s anything you can help with this week

Submit your own request for help

Instill ScienceSeeking collaboratorsPeer preview

The Phage Directory Slack Community

Profile Image
Undergraduate
Liu Lab,
Pomona College

I am a fourth-year undergraduate student at Pomona College where I study molecular biology. I currently research bacteriophage interactions with Vibrio cholerae! After graduating, I hope to continue learning about phage biology, bacterial infections, and phage therapy through a research exchange or a PhD program. I love meeting people in the phage community and would eagerly welcome any opportunities to chat!

Phage Hosts

The Phage Directory Slack community has over ten channels that you and your colleagues can join, from “introductions” to “phage-manufacturing” to “readings” to “random.” Phage Directory is also always open to suggestions for other topics the community wants to discuss and topic channels can be added.

Slack Community Introductions

Introductions

The “introductions” channel is especially great as it is a place for members to introduce themselves and meet new phage phriends. Recently, the “introductions” channel has featured an introduction challenge that has invited members to fill in these prompts and get to know each other:

👋 About me:

🌐 Based in:

👀 What I’m looking for in this community:

🤝 What I can offer:

🤩 Fun Fact:

For example:

From Enrique González Tortuero:

👋 About me: I’m nowadays working as a postdoctoral researcher in the UK in the role of temperate phages of clinic Pseudomonas aeruginosa strains in the host physiology and behavior, mainly focused on the the bioinformatic analyses. I was working previously in phages from my first postdoc in the University College Cork, Ireland (2016 - 2018)

🌐 Based in: Salford, United Kingdom - But who knows where I will be in the future… (Originally I came from Spain, but I was living out of my country for nine years…)

👀 What I’m looking for in this community: Networking with other phage researchers (wet-lab and dry-lab), staying up-to-date in phage research and helping with my (humble and short) experience in bioinformatics applied to microbes and viruses.

🤝 What I can offer: advice on bioinformatics applied to microbes and viruses, including phages obviously

🤩 Fun fact: I can start telling a lot of stories, but I do not want to bother all of you. Let’s say one funny: as a consequence of working with computers for a long time, everybody believes that I am computer scientist or mathematician when I originally studied biology and worked as a lab technician in a plant physiology lab before performing my PhD studies. So, please, do not hesitate to ask to your computer fellows about their background… Maybe you will have a surprise!

Asking Questions

In addition to being a great place to make new phage connections, the Slack community is especially wonderful for asking and answering questions. In each of the topic channels, people can pose questions and members of the community are always eager to answer. Some examples of questions posed by the Slack community:

  1. What is the average molecular weight of bacteriophage particles?
  2. I am interested to get in touch with labs and companies focusing on genetically engineered phages. We are looking for potential collaboration partners for a major pharmaceutical company. Any tips or ideas?
  3. I need some help with Unicycler in Galaxy!
  4. Anyone know the best way to recover phage from freeze-dried ampoules to create laboratory stocks?
  5. I’m super new to bioinformatics and I was wondering what tools should I use if I would like to see the differences between WT bacteria and mutants? What should be the approach? And tools

Group chats and direct messages

Slack also features the ability for community members to create group chats and send direct messages.

Join us!

To join the Slack community, click here: https://phage.directory/slack

Capsid & Tail

Follow Capsid & Tail, the periodical that reports the latest news from the phage therapy and research community.

We send Phage Alerts to the community when doctors require phages to treat their patient’s infections. If you need phages, please email us.

In collaboration with

Mary Ann Liebert PHAGE

Supported by

Leona M. and Harry B. Helmsley Charitable Trust

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