C&T Round Up for March 2022!

Issue 170 | April 1, 2022
3 min read
Capsid and Tail

This week, we highlight the features we published in March! Learn about how to name your phage, how to track your phages, and how to get pheedback from phage peers!

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What’s New

Paper: Phage-inducible chromosomal islands promote genetic variability by blocking phage reproduction and protecting transductants from phage lysis. See also what author Rodrigo Ibarra Chavez has to say about it on twitter: "phage satellites that aren’t that selfish, providing additional benefits to their host cells”!

PICIsPhage-host interactionsResearch paper

Paper: Learn to decipher active prophages from metagenomes using PropagAtE (Prophage Activity Estimator), an automated software tool for estimating if a prophage is in the lytic or lysogenic stage of infection

MetagenomicsProphageResearch paper

Preprint: Bacteriophages Playing Nice: Lysogenic bacteriophage replication is stable in the human gut microbiota

Gut phageLysogenyPreprint

Preprint: Bacteriophages antagonize cGAS-like immunity in bacteria

Phage defense systemsPreprint

Paper: New insights into the structure and assembly of phage P1

Latest Jobs

Mycobacterium phagesResearch specialist
Research Specialist at University of Pittsburgh in the Hatfull Lab to perform advanced experiments in a microbiology laboratory aimed at understanding phages and their infection of Mycobacterium hosts.
Phage TherapyResearch Assistant
Research Assistant to work on a phage therapy project with Assistant Professor John Chen at the National University of Singapore (preferred: students who want to pursue PhD in microbiology). Research in the Chen lab focuses on S. aureus, phages, and pathogenicity islands.

Community Board

Anyone can post a message to the phage community — and it could be anything from collaboration requests, post-doc searches, sequencing help — just ask!

iVoM Season 2, episode #6: Models for Viral Action.
Date: 6 pm CET, April 12th, 2022.
Register at https://ivom.phage.directory

Talks

  • Modeling the Ecological and Therapeutic Impacts of Bacteriophage - an Imperfect Predator, by Prof. Joshua Weitz, Georgia Tech, USA
  • Why are there so many short prophages? The genetic repertoire of active and cryptic prophage sequences, by Prof. Lindi Wahl, Western University, Canada
  • Lord of the Broken Rings: how ATPase ring motors drive genome packaging in dsDNA viruses, by Dr. Marc Morais, Univ. of Texas Medical Branch (UTMB Health), USA

Chairs

  • Dr. Matthias Fischer , Max Planck Institute for Medical Research, Heidelberg, Germany
  • Prof. Corina Brussaard , Royal Netherlands Institute for Sea Research, Netherlands
Virtual EventViruses of microbesiVoM

The 2022 Molecular Genetics of Bacteria and Phages Meeting at University of Wisconsin, Madison is Aug 1-5, 2022 (in person!). Register now!

ConferenceIn personMolecular genetics

You’re invited to Africa Phage Forum #7, which will be a talk called ‘Phage Display - an old resource for new applications’ by Dr. Ivone Martins. The event is currently set to take place the 12th April 2021 at 2pm GMT+3, and will last approximately 1 hour. https://apf.phage.directory/schedule/apf-webinar-7

Africa Phage ForumVirtual Event

There is now a dedicated phage sub-community on Twitter: “Phage Twitter”! Created by Sabrina Green (@Motherofphage on Twitter). Try it out here.

Phage Twitter

C&T Round Up for March 2022!

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Phage microbiologist and co-founder of Phage Directory
Co-founderPostdoctoral Researcher
Skills

Phage characterization, Phage-host interactions, Phage Therapy, Molecular Biology

I’m a co-founder of Phage Directory and have a Ph.D in Microbiology and Biotechnology from the University of Alberta (I studied Campylobacter phage biology). For Phage Directory, I oversee community building, phage sourcing, communications, science, and our awesome team of volunteers.

As of Feb 2022, I’ve recently joined Jon Iredell’s group in Sydney, Australia as a postdoctoral research scientist for the Phage Australia project. I’m diving back into the lab to help get Phage Australia’s country-wide phage therapy system up and running here, working to streamline workflows for phage sourcing, biobanking and collection of phage/bacteria/patient matching and monitoring data, and integrating it all with Phage Directory’s phage exchange, phage alerts and phage atlas systems.

In this month’s Capsid & Tail Monthly Round Up issue, we’re highlighting the three feature articles we published in March. Be sure to check them out if you missed them, and let us know if you have thoughts, comments or questions! Reach us anytime by email or Slack!

C&T Throwback!

There’s lots of great phage stuff in the C&T archive! Check out this article on Engineering phage ΦX174’s genome: a recap of Paul Jaschke’s PHAVES talk by Steph Lynch!


Thanks so much to Atif Khan for collecting links to share for this week!

Capsid & Tail

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Leona M. and Harry B. Helmsley Charitable Trust

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