Micreos, a Dutch/Swiss biotech company, has secured its next funding round of €25 million in growth capital for clinical development of its endolysin technology platform, set to replace antibiotics in many areas.
Adi Millman et al. published a new paper in Cell Host & Microbe entitled An expanded arsenal of immune systems that protect bacteria from phages. They report the discovery of 21 defense systems that protect bacteria from phages, based on computational genomic analyses and phage-infection experiments. Also check out this Twitter thread by the Sorek lab.
In a new paper in mBio, Eugen Pfeifer and colleagues report that phage-plasmids commonly encode different and multiple types of resistance genes of high clinical importance, often in integrons.
In a new paper in Microbiology Spectrum, Aude Ferran (Université de Toulouse) and colleagues report that the combination of phages and antibiotics can prevent the selection of resistant bacteria.
Brendan J. O’Hara (Tufts University School of Medicine) and colleagues published a paper in PLOS Genetics entitled The Vibrio cholerae Seventh Pandemic Islands act in tandem to defend against a circulating phage.