Emily’s Entourage, a nonprofit organization that funds cystic fibrosis research and drug development, has funded four new grants (totaling $790,000 over two years), two of which are phage-related. One was awarded to IPATH researchers to develop a MRSA phage library, and another to Vincent Fischetti for phage lysin development.
Locus Biosciences signed a $144 million contract with BARDA to support phase II and III clinical trials of LBP-EC01, Locus’ CRISPR phage (crPhage™) product.
Adaptive Phage Therapeutics was recognized as a 2020 Champion of Maryland Manufacturing for its efforts to provide emergency phage access to COVID-19 patients with secondary bacterial infections.
Laith Harb (Texas A&M University) and colleagues published a new paper in PNAS showing that host cell penetration by the F-pilus-specific ssRNA phage MS2 triggers detachment of the F-pilus.
Luís Melo (University of Minho, Portugal) and colleagues published a detailed analysis of how the Staphylococcus epidermidis biofilm matrix protects against phage predation.
Xing Wan (KU Leuven and University of Helsinki) and colleagues published a new review in Current Opinion in Biotechnology on phage-based target discovery and its exploitation towards novel antibacterial molecules.